AI agents that turn scientific evidence into product strategy

Centivence is the AI cloud-based platform that centralizes and automatically manages the value and strategy of your products.

Not a dashboard. A workspace where agents work for you.

Centivence is not a place check dashboards. It's where your Marketing, Medical Affairs, and Market Access teams collaborate with specialized agents that act on your behalf, proactively and on demand.

They work without you.

Agents monitor evidence, regulation, and competition around the clock. They surface what matters before you think to ask β€” so your team always starts from the right place.

Ask, Delegate and verify.

Need a competitive summary? Ask CEN. Want to update the value story? Delegate it. Agents act, your team validates. You stay in control without doing the heavy lifting.

One space to align every team.

Marketing, Medical Affairs, and Market Access collaborate in the same workspace with the same agents, the same data, and no duplication. What one team does, the others see instantly.

Search Agent

We keep you updated on new data that is relevant for you.

Set up an agent once. Centivence monitors literature, trial registries, HTAs, and regulatory agencies β€” and alerts your team the moment something relevant surfaces. No manual searches. No missed evidence.

Orzen β€” Orzenic syndrome
Active
Monitoring
Indication Orzenic Syndrome
Keywords
VEXOLIMAB Γ— BRALUKUMAB Γ— TRILANTIZINE Γ— PRAXITINIB Γ— + Add keyword
Expected papers / day
12 Prediction based on last 12 months of activity
Every day at 08:00 you will receive a digest with all new evidence detected β€” nothing missed.

Set it up in seconds

Describe what you want to monitor in plain language. Centivence translates it into a live agent that runs without you.

Learn more β†’

Alerts when it matters

The moment a relevant paper, guideline, or regulatory update is published, your team receives a structured alert β€” with context and suggested next steps.

Learn more β†’
New alert Β· Orzen agent
HIGH IMPACT Journal of Rare Disorders
"Vexolimab vs Bralukumab: 52-week outcomes in Orzenic Syndrome"
Ferrar RJ et al. Β· May 2026
Notebook Β· Orzenic Syndrome 12 papers
What is the primary endpoint result from the Ferrar study?
The primary endpoint was met: Orzen achieved a 68.4% response rate at 24 weeks versus 31.2% for Bralukumab (p<0.001). Secondary endpoints also favoured Orzen.[1]
Compare safety profiles across all saved papers
Ask about your saved papers…
Papers 12
Orzen superiority β€” 52-week RCT
Ferrar et al. Β· 2026
NICE HTA β€” positive opinion
NICE Β· Mar 2026
Bralukumab safety β€” meta-analysis
Whitmore et al. Β· 2026
Real-world β€” Orzenic registry
ORZEN-RWD Β· 2025
Phase II dose-finding study
Chen HK et al. Β· 2024
Notebooks

Your evidence base, always within reach

Save the papers that matter and ask questions directly. Notebooks give your team a shared, structured space to store, explore, and extract value from scientific evidence β€” without leaving the platform.

Add columns to extract structured data from your papers

Pull specific data points β€” endpoints, sample sizes, p-values β€” from every saved paper at once. Build your own evidence table in seconds.

Learn more β†’
Evidence table + Add column
Paper Primary endpoint N p-value
Ferrar et al. 2026 68.4% resp. rate 428 <0.001
Whitmore et al. 2026 31.2% resp. rate 312 0.04
ORZEN-RWD 2025 72.1% at 52w 891 <0.001

No hallucinations β€” every answer is grounded in your evidence

The agent only reasons over the papers you have saved. It never invents data β€” every claim links back to its exact source in your notebook.

Learn more β†’
Agent response Grounded

Based on your 12 saved papers, Orzen shows a consistent superiority in primary efficacy endpoints across both RCT and real-world settings.[1][3]

[1] Ferrar RJ et al. J Rare Disorders 2026
[3] ORZEN-RWD Study Group. 2025
Responses limited to papers in this notebook
Knowledge

All the product context your agents need, always up to date.

Every new paper, regulatory decision, or competitor move is automatically integrated into each product's knowledge profile β€” so your agents always work from the most current picture, without lifting a finger.

app.centivence.com/knowledge
Knowledge
Orzen
Orzenic syndrome
3
Kalzupine
Phase III
Vexolimab
Post-approval
1
Fervatinib
Pre-launch
Praxitinib
Discovery
Orzen β€” Orzenic syndrome
Updated 2h ago
Efficacy
Safety
Economic
Endpoint Orzen (n=214) Comparator p-value Ref
Overall response rate (ORR)
Primary endpoint Β· Week 24
68.4% 31.2% Bralukumab p<0.001 [1]
Disease-free survival (median)
Secondary endpoint
22.3 mo 14.1 mo Bralukumab p=0.004 [1][2]
Time to first response
Secondary endpoint
6.2 wk 9.8 wk Trilantizine p=0.012 [2]
Patient-reported outcomes (DLQI)
Secondary endpoint
βˆ’11.4 pts βˆ’6.8 pts Bralukumab p<0.001 [3]
Treatment discontinuation rate
Exploratory
4.1% 8.7% Bralukumab p=0.08 [1]
[1] Ferrar RJ et al. J Rare Disorders 2026;14(3):112–128.
[2] Whitmore AS, Tanaka KH. Clin Evid Rev 2025;9(1):44–57.
[3] Bouchard ML et al. PRO Quarterly 2025;6(4):88–99.

Always current

New publications, decisions, and competitor moves are integrated automatically into each product profile β€” in real time.

Product-level intelligence

Every molecule has its own profile: evidence, regulatory status, competitor landscape, and market access β€” all in one place.

Shared across teams

Marketing, Medical Affairs, and Market Access work from the same updated knowledge β€” no duplication, no version conflicts.

Insight-ready

Each update comes tagged by impact and relevance β€” so your team knows immediately what requires attention and what can wait.

Question
What is the comparative efficacy of Vexolimab vs Bralukumab in patients with Orzenic Syndrome at week 52?
191 articles found
Summarising papers
Generating response
Answer

At week 52, Vexolimab demonstrated a statistically significant improvement in primary endpoints compared to Bralukumab [1]. Response rates were 68% vs 51% [2], with a comparable safety profile across both arms [1,3].

[1] Ferrar RJ et al. J Rare Disorders Β· 2025
[2] Bouchard ML et al. Clin Evid Rev Β· 2025
[3] Whitmore AS et al. Int J Pharmacol Β· 2024
Find Papers

Ask your agent and get the answer, not the papers

Ask in plain language. Centivence searches across 232M+ published papers and returns an answer grounded in the evidence that best matches your question. Every insight comes with its reference, the relevant text excerpt, and a link to the original source β€” fully auditable, zero hallucination.

Millions of sources. One search.

Your question reaches PubMed, clinical trial registries, HTA databases, and regulatory sources simultaneously β€” in seconds, without leaving Centivence.

Learn more β†’
232M+ publications indexed
PubMed
ClinicalTrials.gov
EMA / FDA
HTA databases
Cochrane
ISPOR
Continuously expanding Β· Last indexed 2h ago

Every answer, fully traceable.

Each insight is linked to its source paper, the exact passage it comes from, and a direct link to the original. Bring any answer to a payer meeting, a dossier, or a regulatory submission β€” with full confidence.

Learn more β†’
Traceable answer

Response rates were 68% vs 51% at week 52, with a comparable safety profile across both treatment arms.

Ferrar RJ et al., J Rare Disorders 2025, p. 4
View original β†’
Text excerpt
Value Creator

Mantain updated your product messaging

When a relevant article is detected, the agent recognises, stores, and transforms it into a ready-to-use strategic message β€” always traceable to the original source.

Value Narratives 4 active
3 new articles detected that could update 2 of your narratives Review
Orzen value narrative
Phase III efficacy Β· Updated Mar 2026
2 new articles
Orzenic Syndrome GVD
Economic value Β· Feb 2026
Up to date
Orzen payer value narrative
Long-term safety Β· Dec 2025
1 new article
KOL Engagement Pack
Scientific communication Β· Nov 2025
Up to date

Automatically detect and prioritise relevant evidence

The system monitors new publications continuously and flags those with high relevance for your products β€” no manual searches needed.

Learn more β†’
New detections
Today Week Month
Orzen superiority confirmed β€” 52-week RCT
Ferrar RJ et al. Β· J Rare Disorders Β· May 2026
High impact
Bralukumab Phase III results β€” EADV Congress
Conference abstract Β· May 2026
Monitor
NICE positive opinion β€” HTA submission accepted
NICE Β· Regulatory Β· Mar 2026
HTA

Just tell it, and it will generate tailored messaging

In seconds, build a full scientific narrative aligned with your strategy β€” from a single article to a complete, ready-to-use value story.

Learn more β†’
Narrative Β· Market Access Traceable

Phase III data establishes Orzen as the new standard of care in Orzenic Syndrome, with a 68.4% response rate at 24 weeks versus 31.2% for Bralukumab (p<0.001)[1] and a median disease-free survival of 22.3 months[1][2] β€” supporting a compelling argument for formulary inclusion.

[1] Ferrar RJ et al. J Rare Disorders 2026;14(3):112–128.
[2] Whitmore AS, Tanaka KH. Clin Evid Rev 2025;9(1):44–57.

Ready to transform your evidence management?

Join leading teams who are already using Centivence to centralize and automate their product strategy.

Book Demo

A system where everything works together.

Centivence connects key scientific workflows across departments into one intelligent system. Less fragmentation, faster decisions powered by real evidence.

Marketing Teams

Brand strategy, messaging, and competitive positioning always backed by the latest evidence β€” without chasing updates across six inboxes.

Medical Affairs Teams

Scientific narrative, publication plans, and MSL field tools built from a single evidence base that updates itself.

Market Access teams

Dossiers, value stories, and payer arguments updated automatically as new evidence surfaces β€” always submission-ready.

Transform the way you manage evidence

We are the first AI software for the healthcare sector designed to work for you. Centivence keeps you ahead with the latest publications in your field β€” helping you search, analyze, and classify scientific evidence in seconds.

Do you spend too much time with evidence?

Our platform frees healthcare professionals from countless manual hours, giving you back the time to focus on what truly matters: strategic thinking and impactful decisions.

24/7
A system that works for you, continuously

Set up a continuous evidence monitoring system in minutes. Centivence tracks new publications and competitor data around the clock so you never miss critical updates.

10x
Execute evidence strategies faster

Move from scattered documents to a structured evidence system. Within Centivence, teams analyze, compare, and act on evidence in one place, accelerating strategic workflows.

75%
Less manual work across evidence workflows

Stop switching between Excel files, PDFs, and external AI tools. Centivence understands your objectives and evidence scope, tailoring insights to your priorities while centralizing tracking and analysis in a single workspace.

Head of Medical Affairs
Top-20 Pharmaceutical Company Β· Europe
"Our MSL team were losing time reviewing new papers and preparing their medical conversations. With Centivence, they can now focus their time on higher value tasks."

Frequently asked questions

Have more questions? Send us an email.

What is Centivence and what problem does it solve?

Centivence is an AI-powered evidence management platform built for healthcare teams. It helps transform scattered scientific evidence into structured, traceable knowledge that teams can actually use for strategy, decision support, and value creation.

What types of data can Centivence search and organize?

Centivence works with scientific publications, competitive evidence reports. It focuses on structured scientific content rather than general web information.

Where does Centivence get its scientific evidence from?

Centivence navigates large scientific literature sources such as PubMed and Semantic Scholar and more sources coming soon, ensuring that all insights are grounded in verifiable sources.

How do healthcare professionals use Centivence?

They can use Centivence to find, track, organize, and analyze scientific publications relevant to their indications of interest. They can create custom baskets for different projects, apply labels for easy categorization, and use the AI assistant to extract insights and generate summaries from the literature.

What is Centivence not a good fit for?

Centivence is not designed for general document management, consumer health information, or non-scientific content. It's specifically optimized for working with scientific publications and evidence.

Does Centivence provide citations and source traceability?

Yes. Every insight and answer generated by Centivence is linked to its original source, allowing teams to verify, review, and audit the underlying evidence at any time.

Why do pharmaceutical companies need scientific evidence management software?

Having a scientific evidence management software allows organizations to centralize, structure, and reuse the scientific knowledge they generate and consume every day. Instead of working with scattered PDFs, shared folders, or repetitive manual searches, teams can access contextualized, traceable information ready to support strategic decisions. Less time managing evidence, more time turning it into real impact.

How can you get in contact with the team?

You can reach our team by emailing info@centivence.com or by using the contact form on our website. We typically respond within 24 hours on business days.

Stop managing evidence.
Start using it.

See how Centivence gives your Medical Affairs, Marketing, and Market Access teams a single system to find, organise, and act on scientific evidence.

Book a demo